Including:
Organic Silica, Organic Magnesium, Resveratrol, Hyaluronic Acid, , Superoxide Dismutase
(SOD), Collagen, Amino Acids (Alanine, Histidine), Zinc Oxide USP, Acai,
Rhodiola Rosea, Sweet Almond Oil, Olive Oil, Jojoba Oil, Rheosol, Uniphen.
Although we
could include volumes of information on each unique individual ingredient
included in the Doctor’s Beyond Resveratrol® cream, at this point in time we are
proud to share educational information on the remarkable resveratrol. Educated
consumers make better decisions.
Please Be Advised:
Information contained on our website is for educational purposes only and is not intended to diagnose, treat, cure or prevent any disease. This information has not been evaluated by the Food and Drug Administration (FDA). No claims and no systemic medical claims are made nor implied for the use of this product.
Doctor’s Beyond
Resveratrol® cream was formulated by United States patent holder Dr. Charles
Mesko to go “beyond” existing skincare products. Our loyal customers consider Doctor’s Beyond
Resveratrol® cream to be the finest skin care product available. Extremely
pleased women report that this single product eliminated the need for using one or more expensive
over-the-counter skin care
products including:
moisturizers, eye puffiness creams, wrinkle creams, age-spot creams, skin
tightening creams, fine line creams and deep wrinkle creams.
Doctor’s
Beyond Resveratrol® cream is considered by natural doctors and our
satisfied customers to be a very effective product. Our skin care product
is formulated to go “beyond” existing expensive skin care cosmetics and costly over-the-counter
skin products to offer skin support to sun damaged, prematurely aged, wrinkled,
or malnourished skin on the face, neck and body. It is estimated that 80% of skin damage is caused by the sun.
Originally prompted by the
“French Paradox”, the study of resveratrol is the subject of ongoing worldwide
clinical research. The French paradox is the
observation that the French suffer a relatively low incidence of coronary heart
disease, despite having a diet relatively rich in saturated fats. The
phenomenon was first noted by Irish physician Samuel Black in 1819. When a description of this paradox was aired
in the United States on 60 Minutes in
1991 with the proposal that red wine decreases the incidence of cardiac
diseases, the consumption of red wine increased 44%. In 2002, the average
French person consumed 108 grams per day of fat from animal sources while the
average American consumed only 72. The French eat four times more butter, 60
percent more cheese and nearly three times more pork. Although the French
consume only slightly more total fat, they consume much more saturated fat
because Americans consume a much larger proportion of fat in the form of
vegetable oil, with most of that being soybean oil. According to data from the
British Heart foundation, rates of death in 1999 from coronary heart disease
among males aged 35–74 years was 115 per 100,000 people in the U.S. but only 83
per 100,000 in France.
Resveratrol is a phytoalexin
(or antibiotic) produced naturally by plants when under attack by pathogens
such as bacteria or fungi. It is usually sold as a dietary supplement, but is
best known as an element contained in red wine. In grapes, resveratrol is found
primarily in the skin and in the seeds. The amount found in grape skins also
varies with the type of grape, its geographic origin, and exposure to fungal
infection. The amount of fermentation time a wine spends in contact with grape
skins is an important determinant of its resveratrol content. In experiments on
mice and rats, anti-cancer, anti-inflammatory, blood-sugar-lowering and other beneficial cardiovascular effects
of resveratrol have been reported.
The groups of Howitz and
Sinclair reported in 2003 in the journal Nature
that resveratrol significantly extended the lifespan of the yeast Saccharomyces cerevisiae. Later studies
conducted by Sinclair showed that resveratrol also prolonged the lifespan of
the worm Caenorhabditis elegans and
the fruit fly Drosophila melanogaster. In 2006, Italian scientists obtained the
first positive result of resveratrol supplementation in a vertebrate. Using a
short-lived fish with a median life span of nine weeks, they found that
resveratrol increased the median lifespan by 56%. Compared with the control
fish at nine weeks, the resveratrol-supplemented fish showed significantly
higher general swimming activity and better learning to avoid an unpleasant
stimulus.
Sinclair later reported that
resveratrol counteracted the
detrimental effects of a high-fat diet in mice. The
high fat diet (from adding hydrogenated coconut oil to the standard diet),
provided 60% of energy from fat, and the mice on it consumed about 30% more
calories than the mice on the standard diet. Both the mice fed the standard
diet and the high-fat diet plus resveratrol had a 30% lower risk of death than the mice on the high-fat diet. Insulin and glucose levels in
mice on the high-fat resveratrol diet were closer to the mice on standard diet
than the high-fat mice. Adding
resveratrol to the diet of mice inhibit
muscle aging and age-related cardiac dysfunction. In 2008, a study found that high doses
of resveratrol (a constituent of red wine) mimicked some of the benefits of
caloric restriction (including reduced effects of aging) in mice.
The study supported
Sinclair's hypothesis that the effects of resveratrol are due to the activation
of the Sirtuin 1 gene (or SIRT1). Responsible for cellular regulation, sirtuins
regulate important biological pathways. They influence aging, stress
resistance, assisting in the repair of DNA, and regulating genes that undergo
altered expression with age. In a study of 123 Finnish adults, those born with
certain increased variations of the SIRT1 gene had faster metabolisms, helping
them to burn energy more efficiently—indicating that the same pathway shown in
the lab mice works in humans.
In 1997, it was reported
that topical resveratrol applications
prevented the development of skin cancer in mice treated with a carcinogen.
There have since been dozens of studies of the anti-cancer activity of resveratrol in animal models. The whole body effectiveness of resveratrol is limited by
its poor systemic bioavailability. Thus,
topical application of resveratrol in mice, both before and after UVB exposure,
inhibited the skin damage and decreased skin cancer incidence. However, oral
resveratrol was ineffective in treating mice inoculated with melanoma cells. In humans, about 70% of
resveratrol given as a pill is absorbed; however, it is rapidly metabolized in
the intestines and in the liver. Only trace amounts of resveratrol can be
detected in the blood after an oral dose. Resveratrol from wine is even less
effective: its highest level in the bloodstream is minimal, and it completely
disappears after approximately four hours. As evidenced by the mice
experiments, topical application is thought to be the most efficient method of
delivery. Resveratrol is thought to work at the metabolic level, stimulating
the cells’ anti-aging genes through its genetic, metabolic and biochemical
mechanisms.
DISCLAIMER: Ideas and information contained above are based on
years of experience by Dr. Charles Mesko, professional colleagues, and research
conducted throughout the world, with extensive review of scientific literature.
The above information is for educational purposes only and is not intended as a
basis for diagnosis, treatment, or to cure any disease. These statements have not been evaluated by
the Food and Drug Administration (FDA). This information is not intended to be a
substitute for careful medical evaluation and treatment by a competent and
licensed health care professional. Dr. Charles Mesko, Doctor’s Relief, LLC,
and/or Fountain of Youth Technologies, Inc., strongly recommend that you do not change any current
medications or add any new therapies without personally consulting a fully
qualified and licensed health care professional. Dr. Charles Mesko, Doctor’s
Relief, LLC, Fountain of Youth Technologies, Inc., employees, staff and
associated personnel specifically disclaim any liability arising directly or
indirectly from inappropriate use of contained information.
